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Medication-Assisted Treatment (MAT) Treatment Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for a comprehensive approach to addiction treatment.

Found 173 treatment centers offering medication-assisted treatment (mat) across Massachusetts.

Last reviewed: March 27, 2026

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Showing 13 of 173 medication-assisted treatment (mat) treatment centers

The North Charles Institute, situated in Cambridge, MA, specializes in outpatient detoxification and treatment programs for individuals aged 18 and older, including both adults and young adults. This facility emphasizes personalized care, offering a range of services such as brief intervention, substance use disorder counseling, and outpatient treatment using methadone, buprenorphine, or naltrexone. Designed to address the specific requirements of each individual, the center provides support for both men and women who are seeking guidance and assistance in their recovery process. At the North Charles Institute, clients can expect a compassionate approach tailored to facilitate their journey towards healing.

The North Charles Institute, situated in Cambridge, MA, offers a range of outpatient services including detoxification, substance use treatment, and specialized programs designed specifically for adults facing co-occurring serious mental health disorders. Utilizing evidence-based methodologies such as cognitive behavioral therapy and contingency management, this facility addresses the complexities of addiction and mental health. Catering primarily to adult men, the center also provides treatment options for young adults dealing with serious emotional disturbances. With access to outpatient therapies that include methadone/buprenorphine or naltrexone, the North Charles Institute strives to offer comprehensive support for individuals navigating their recovery journey. The facility emphasizes personalized care, adapting its approach to the distinct needs of all clients, fostering a nurturing and supportive environment conducive to healing and personal development.

Open Sky Community Services, situated in Douglas, Massachusetts, provides long-term residential care alongside 24-hour support for both adults and young adults facing challenges related to substance use and co-occurring serious mental health conditions. The center employs a combination of therapeutic approaches, including cognitive behavioral therapy, anger management, and motivational interviewing, to address the unique needs of individuals who have undergone trauma, as well as those affected by domestic violence, intimate partner violence, or sexual abuse. With customized programs available for male and female clients, Open Sky Community Services focuses on delivering quality care and fostering holistic healing, ensuring a nurturing environment for individuals on their path to recovery.

Situated in Lawrence, MA, the Psychological Center delivers a variety of specialized addiction treatment services designed specifically for adult women. The facility offers multiple treatment options, including long-term residential care, outpatient programs, and outpatient services utilizing methadone, buprenorphine, or naltrexone. A key aspect of the center’s approach involves 12-step facilitation, as well as anger management and brief intervention techniques. In addition to its primary services, the center features tailored programs for adolescents, adult women, and individuals who have faced intimate partner violence or domestic violence. With an inclusive focus that serves adults, seniors, and young adults, the center emphasizes specialized care for women, highlighting its commitment to providing comprehensive and compassionate support for those on the path to recovery from substance use disorders.

Situated in Norwood, Massachusetts, the Riverside OP Center at Norwood provides targeted outpatient treatment for individuals dealing with substance use issues as well as co-occurring mental health disorders. The center employs therapeutic methods such as cognitive behavioral therapy, motivational interviewing, and strategies aimed at relapse prevention, ensuring that care is customized to meet the distinct needs of each client. Programs are available for both adults and children, including adolescents, allowing for a holistic approach to recovery that is inclusive of all genders. Additionally, the facility offers outpatient treatment options that include methadone or buprenorphine, as well as naltrexone, placing a strong emphasis on delivering quality care tailored to support individuals throughout their path to achieving sobriety.

SMOC Behavioral Healthcare, located in Framingham, MA, provides targeted treatment for adults dealing with substance use issues and co-occurring serious mental health disorders, as well as services for children facing serious emotional disturbances. The center offers long-term residential care and 24-hour support, integrating techniques such as 12-step facilitation, anger management, and brief intervention strategies. There are distinct programs designed to meet the needs of various groups, including active duty military personnel, adult women, and individuals who have encountered intimate partner violence or domestic violence. While serving a diverse clientele that includes adults, seniors, and young adults, the facility places particular emphasis on addressing the unique needs of female clients, fostering a comprehensive and nurturing environment conducive to recovery and wellness.

New Bedford, MA

SOAR, based in New Bedford, MA, serves as a comprehensive rehabilitation facility that provides outpatient treatment for substance use disorders to both adults and young adults. This center specializes in addressing co-occurring substance use disorders and serious mental health conditions, recognizing the complex interplay between these issues. Utilizing strategies such as 12-step facilitation, anger management, and brief intervention, SOAR tailors its programs to the unique needs of each individual. The facility offers specific programs designed for active duty military members, as well as separate services for adult men and women. In addition, SOAR provides outpatient treatment options that include methadone, buprenorphine, and naltrexone, ensuring that both male and female clients have access to effective care as they navigate their recovery journeys.

The South Middlesex Opportunity Council, located in Millbury, MA, provides dedicated addiction treatment services within a nurturing and secure setting. The center features long-term residential care options, which include transitional housing and sober living arrangements. Emphasizing methods such as 12-step facilitation, anger management, and brief interventions, the facility specifically supports adult women who have faced intimate partner violence, domestic violence, or sexual abuse. Catering to a diverse range of individuals, including adults, seniors, and young adults, the program is designed to meet the distinct needs of female clients. Through its holistic approach and specialized offerings, the center aims to deliver effective care for those pursuing recovery from substance use disorders.

Fall River, MA

SSTAR, situated in Fall River, Massachusetts, is a rehabilitation center dedicated to the treatment of substance use disorders. The facility provides outpatient services that include treatment with methadone, buprenorphine, or naltrexone. It employs evidence-based methodologies such as 12-step facilitation, brief intervention, and cognitive behavioral therapy to support its clients. This center serves a diverse range of populations and offers specialized programs for active duty military personnel, as well as tailored services for adult men and women. With a focus on individualized care, SSTAR is equipped to assist both adults and young adults, ensuring that treatment is responsive to the unique needs of each male and female client. The organization's commitment to quality care aims to guide individuals on their recovery journey.

Fall River, MA

SSTAR, situated in Fall River, Massachusetts, provides a variety of evidence-based treatment options for individuals dealing with substance use disorders and co-occurring mental health issues. The facility offers intensive outpatient programs, outpatient services, and day treatment, all of which include a blend of 12-step facilitation, anger management, and brief intervention strategies. Tailored programs are also available for those who have faced intimate partner violence, domestic abuse, sexual assault, and trauma. Serving adults and young adults across all genders, SSTAR is committed to delivering individualized care and support to aid clients on their journey toward sustained recovery. The center emphasizes a comprehensive approach, making it a valuable resource for those in search of rehabilitation services.

Fall River, MA

Located in Fall River, MA, Steppingstone Inc provides outpatient treatment for substance use, along with specialized services for those who are facing both substance use issues and serious mental health conditions, including emotional disturbances. Their offerings encompass a range of therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy. The facility is dedicated to serving adult men and women, including individuals who have encountered experiences related to intimate partner or domestic violence. With an emphasis on adults and young adults of all genders, Steppingstone Inc aims to deliver personalized care that supports clients as they progress on their path to recovery.

Dorchester, MA

Victory Programs Inc, situated in Dorchester, MA, provides a variety of services aimed at supporting women who are dealing with substance use disorders and related issues. The facility offers long-term residential treatment within a nurturing environment, emphasizing 12-step facilitation, anger management, and cognitive behavioral therapy. Catering specifically to adult women, the center has special programs designed for individuals who have faced intimate partner violence, domestic violence, and sexual abuse. Victory Programs Inc is committed to delivering effective care for both adult and senior women seeking recovery in a space that acknowledges their unique experiences. This center serves as an important resource for those in need of transitional housing, halfway house services, or sober living arrangements.

VOA Behavioral Health Services, located in Taunton, MA, provides outpatient treatment for adults facing substance use challenges alongside serious mental health conditions. The center offers a range of specialized services, including anger management, cognitive behavioral therapy, and brief interventions, all designed to address the unique needs of its clients. Programs are available for adolescents, as well as adult men and women, ensuring that various age groups receive the appropriate care. In addition to regular outpatient services, the facility offers methadone and buprenorphine treatments. It serves both male and female clients, including seniors, reflecting its commitment to delivering quality care throughout the recovery process. VOA Behavioral Health Services remains dedicated to supporting individuals as they navigate their path to recovery.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to provide a comprehensive approach to substance use disorders. Recognized as the gold standard for opioid addiction treatment by the World Health Organization, SAMHSA, and the American Society of Addiction Medicine, MAT has been proven to reduce overdose deaths, improve treatment retention, and support long-term recovery. Massachusetts has been a national leader in expanding MAT access as part of its response to the opioid crisis.

Understanding MAT

MAT works by targeting the brain's opioid receptors or reward pathways to reduce cravings, prevent withdrawal symptoms, and block the euphoric effects of addictive substances. It is not simply "replacing one drug with another" — MAT medications are prescribed at controlled doses that stabilize brain chemistry, allowing individuals to function normally, engage in therapy, maintain employment, and rebuild their lives.

Key principles of MAT:

  • Medication addresses the biological component of addiction while therapy addresses psychological and behavioral components
  • Treatment should be individualized — no single medication works best for everyone
  • Duration of treatment varies; many individuals benefit from long-term or indefinite MAT
  • MAT should always include counseling and psychosocial support, not medication alone
  • Stopping MAT prematurely is associated with significantly higher relapse rates

Types of MAT Medications

For Opioid Use Disorder

Three FDA-approved medications are available for opioid addiction:

  • Methadone: A full opioid agonist that eliminates withdrawal symptoms and reduces cravings. Dispensed through certified Opioid Treatment Programs (OTPs). Requires daily visits initially, with take-home doses earned over time. Most effective for severe opioid use disorder and individuals who haven't responded to other medications.
  • Buprenorphine (Suboxone, Sublocade): A partial opioid agonist that reduces cravings and withdrawal with lower overdose risk than methadone. Available as sublingual tablets/films (Suboxone), monthly injections (Sublocade), and implants (Probuphine). As of 2023, any licensed prescriber can prescribe buprenorphine — the previous X-waiver requirement has been eliminated, significantly expanding access.
  • Naltrexone (Vivitrol): An opioid antagonist that completely blocks opioid effects. Available as monthly injection (Vivitrol) or daily oral tablet. Requires complete opioid detox before starting (typically 7-14 days). Ideal for highly motivated individuals and those in criminal justice settings.

For Alcohol Use Disorder

Three FDA-approved medications are available for alcohol addiction:

  • Naltrexone: Reduces the pleasurable effects of alcohol and decreases cravings. Available as daily oral tablet or monthly injection (Vivitrol).
  • Acamprosate (Campral): Helps restore the balance of brain chemicals disrupted by chronic alcohol use, reducing anxiety and insomnia in early recovery.
  • Disulfiram (Antabuse): Creates an unpleasant physical reaction (nausea, flushing, headache) when alcohol is consumed, serving as a deterrent. Requires high motivation and compliance.

MAT Availability in Massachusetts

Massachusetts has been a leader in MAT expansion, driven by the severity of the opioid crisis in the state:

  • Multiple certified Opioid Treatment Programs (OTPs) provide methadone across the state
  • With the elimination of the X-waiver requirement, any licensed prescriber can now prescribe buprenorphine, dramatically expanding office-based access
  • Many Massachusetts emergency departments now initiate buprenorphine treatment, connecting patients directly to ongoing care
  • MassHealth covers all FDA-approved MAT medications with no prior authorization required
  • The state's Bureau of Substance Addiction Services funds MAT services for uninsured individuals
  • Mobile MAT units and telehealth prescribing have expanded access to rural and underserved areas

Is MAT Right for You?

MAT may be appropriate if you:

  • Have a moderate to severe opioid or alcohol use disorder
  • Have experienced relapse after previous treatment attempts
  • Want to reduce cravings and withdrawal symptoms while engaging in therapy
  • Need to maintain work, school, or family responsibilities during treatment
  • Are at high risk for overdose

The decision to start MAT should be made collaboratively with an addiction medicine provider who can assess your specific needs, medical history, and treatment goals. MAT works best when combined with CBT, motivational interviewing, group therapy, and peer support.

Common Misconceptions About MAT

  • "MAT is just replacing one addiction with another" — False. MAT medications are prescribed at stable doses that normalize brain chemistry without producing euphoria. They allow individuals to function normally, unlike addictive substance use.
  • "You're not really sober if you're on MAT" — This harmful misconception discourages people from seeking effective treatment. MAT is evidence-based medical treatment, just like insulin for diabetes or antidepressants for depression.
  • "MAT is a short-term fix" — Research shows that longer durations of MAT are associated with better outcomes. Many individuals benefit from MAT for years, and there is no medical reason to set arbitrary time limits.
  • "MAT medications are easy to misuse" — Buprenorphine has a ceiling effect that limits its potential for abuse. Naltrexone has no abuse potential. Methadone is dispensed in controlled settings.

Frequently Asked Questions

How long do I need to be on MAT?

There is no standard duration. Some individuals use MAT for months, others for years. The National Institute on Drug Abuse recommends at least 12 months for opioid use disorder, but many experts support indefinite treatment when it is working well. Tapering decisions should be made carefully with your provider.

Can I still attend 12-step meetings while on MAT?

Absolutely. While some 12-step meetings have historically been less accepting of MAT, attitudes are changing. Many MAT-friendly meetings exist, and SMART Recovery fully supports MAT as part of recovery. The official positions of AA and NA do not prohibit medication prescribed by a doctor.

Does MassHealth cover MAT?

Yes. MassHealth covers all three FDA-approved MAT medications for opioid use disorder and alcohol use disorder without prior authorization. Most commercial insurance plans in Massachusetts also cover MAT under state and federal parity laws.

Can I drive and work while on MAT?

Yes. Once stabilized on MAT, most individuals can safely drive, work, and engage in all normal daily activities. Federal law protects individuals on MAT from employment discrimination under the Americans with Disabilities Act.

What happens if I relapse while on MAT?

Relapse does not mean treatment failure. Your provider may adjust your medication dose, add or change therapy, or modify your treatment plan. The important thing is to continue with treatment rather than stopping MAT, which would increase overdose risk.

For more information about MAT:

Find MAT providers in Massachusetts through our treatment center directory, or call the Massachusetts Substance Use Helpline at 1-800-327-5050 for referrals.