Medication-Assisted Treatment (MAT) Treatment Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for a comprehensive approach to addiction treatment.
Found 173 treatment centers offering medication-assisted treatment (mat) across Massachusetts.
Last reviewed: March 27, 2026
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Showing 20 of 173 medication-assisted treatment (mat) treatment centers

Spectrum Health Systems Inc, located in Worcester, MA, specializes in outpatient treatment tailored for adults dealing with substance use and co-occurring serious mental health issues, as well as addressing emotional disturbances in children. The center employs a variety of therapeutic methods, such as anger management techniques, cognitive behavioral therapy, and brief interventions, to support its clients. Notably, the facility has programs designed specifically for active duty military personnel, as well as for adult men and women. With a primary focus on adults and young adults of all genders, Spectrum Health Systems Inc strives to offer effective care through outpatient services, including the use of methadone or buprenorphine, naltrexone treatments, and structured regular outpatient programs. The organization is committed to delivering comprehensive and personalized care aimed at supporting individuals on their path to recovery.

Spectrum Health Systems Inc., located in Weymouth, MA, provides a range of services focused on treating substance use disorders. Their offerings include outpatient treatment, as well as outpatient programs specifically using methadone, buprenorphine, or naltrexone. The facility implements evidence-based methods such as cognitive behavioral therapy, contingency management with motivational incentives, and motivational interviewing. This comprehensive approach supports both adult men and women, including individuals who have faced intimate partner violence or domestic violence. Spectrum Health Systems Inc. is committed to delivering personalized care to adults and young adults of all genders, fostering a nurturing environment aimed at promoting sustainable recovery.

Youth Opportunities Upheld Inc, based in Worcester, MA, provides outpatient treatment for individuals dealing with substance use issues, as well as those facing serious mental health challenges that often occur alongside these conditions. The facility employs a range of evidence-based treatment methods, including cognitive behavioral therapy and motivational interviewing, to deliver regular outpatient services. Designed to accommodate both adults and children or adolescents, the center also features specialized programs aimed at supporting clients who have experienced intimate partner violence, domestic violence, and sexual abuse. With a commitment to serving male and female clients alike, the organization focuses on offering comprehensive care and personalized interventions to assist individuals on their recovery journey.

Situated in Webster, MA, Harrington Hospital Outpatient is dedicated to providing thorough substance use treatment services for adults, including individuals grappling with co-occurring mental health issues. The center offers a range of options, including intensive outpatient programs and standard outpatient care, as well as treatment alternatives such as methadone, buprenorphine, or naltrexone. Emphasizing therapeutic approaches such as anger management, brief intervention, and cognitive behavioral therapy, the facility serves a diverse population, including active duty military members and adult men and women. Committed to delivering quality care, Harrington Hospital Outpatient tailors its specialized programs to accommodate the unique needs of adults and young adults of all genders.

Healthcare Resource Centers, situated in Westfield, MA, provides outpatient treatment for substance use disorders through evidence-based methods. These include cognitive behavioral therapy, motivational interviewing, and contingency management. The facility has tailored programs specifically designed for active duty military personnel as well as for adult men and women. Catering primarily to adults and young adults regardless of gender, the center offers outpatient services that encompass the administration of methadone, buprenorphine, or naltrexone. Healthcare Resource Centers aims to deliver personalized care and treatment to assist individuals on their journey toward recovery from addiction.

The OnCall Healthy Living Program, situated in Northampton, MA, provides a range of outpatient services including detoxification and treatment for substance use disorders, along with methadone, buprenorphine, or naltrexone options. This facility has a particular focus on brief interventions, cognitive behavioral therapy, and the use of contingency management techniques coupled with motivational incentives. Serving adults and young adults of all genders, the program pays special attention to the needs of pregnant and postpartum women. The center emphasizes personalized care within a supportive environment, aiming to assist individuals as they navigate their recovery process. If you or someone you know is in need of addiction treatment, the OnCall Healthy Living Program offers a commitment to supporting the pursuit of sustained sobriety.

The OnCall Healthy Living Program, located in Indian Orchard, MA, provides outpatient detoxification and substance use treatment specifically designed for adults and young adults. The center places a strong emphasis on the needs of pregnant and postpartum women, offering specialized care within a safe and supportive setting. To address various aspects of recovery, treatment modalities include brief interventions, cognitive behavioral therapy, and motivational incentives. The facility is dedicated to delivering quality care and offers outpatient treatments involving methadone, buprenorphine, or naltrexone. By accommodating both male and female clients, the program ensures that treatment plans are tailored to the unique needs of each individual, fostering an environment conducive to recovery and healthy living. For those seeking comprehensive addiction treatment, the OnCall Healthy Living Program aims to provide the necessary support.

Umass Harrington Healthcare at Webster, situated in Webster, Massachusetts, specializes in outpatient treatment aimed at addressing substance use issues and co-occurring serious mental health disorders in adults, alongside emotional disturbances in children. The facility adopts a comprehensive approach to care, utilizing methods such as anger management, cognitive behavioral therapy, and personalized programs that cater to the unique needs of each client. Focusing on both young and adult individuals, the center offers services to male and female clients. Treatment options available at this facility encompass outpatient methadone or buprenorphine therapy, naltrexone treatment, regular outpatient services, and brief interventions. Committed to providing quality care with tailored approaches, Umass Harrington Healthcare at Webster supports individuals in their recovery journey.

CleanSlate Centers, located in Leominster, MA, provides outpatient treatment for substance use disorders. The facility offers a range of services, including outpatient options involving methadone, buprenorphine, or naltrexone therapy. Emphasizing techniques such as motivational interviewing and relapse prevention, CleanSlate Centers develops personalized treatment programs aimed at both adults and young adults. The center accommodates clients of all genders, ensuring that each person receives care that meets their specific needs. With a focus on creating a supportive environment, the experienced staff at CleanSlate Centers is dedicated to delivering quality treatment to facilitate lasting recovery. If you're looking for specialized addiction treatment, CleanSlate Centers serves as a significant resource during your recovery process.

Situated in Springfield, MA, Clinical and Support Options Inc provides a wide range of outpatient services aimed at individuals who are looking for detoxification and treatment for substance use issues. The facility has a particular emphasis on addressing co-occurring disorders, which allows it to offer outpatient detox programs alongside treatments involving methadone and buprenorphine. The therapeutic approaches employed at this facility include methods such as anger management and cognitive behavioral therapy, catering to the diverse needs of clients. Programs are specifically designed for adult men and women, including those who have faced intimate partner violence. The center prioritizes the care of both adults and seniors, offering gender-specific treatment options to enhance the personal relevance of the services provided. With a commitment to delivering quality care and individualized support, Clinical and Support Options Inc works to facilitate the journey toward sustainable recovery for its clients.

Elm Tree Clinic, situated in Malden, MA, provides targeted outpatient services for individuals dealing with substance use and co-occurring disorders, encompassing both adults and children. The clinic emphasizes relapse prevention and personalized care, offering a variety of services such as substance use counseling and telemedicine therapy. Elm Tree Clinic is distinctive for its customized treatment strategies, designed to meet the needs of adults and young adults across all genders. Clients can access regular outpatient services alongside methadone or buprenorphine treatment as part of a supportive framework aimed at fostering long-term recovery.

Middlesex Recovery PC, located in Stoughton, MA, provides specialized outpatient treatment programs aimed at addressing substance use concerns for both adults and young adults. The center employs a variety of evidence-based treatments, which include cognitive behavioral therapy, motivational interviewing, and counseling for substance use disorders. Prioritizing individualized care, Middlesex Recovery PC ensures that each client receives focused and personal attention tailored to their unique situation. Additionally, they offer outpatient options involving methadone, buprenorphine, and naltrexone to meet the varying needs of their clients. The facility is open to both men and women who are in search of effective and understanding support for their addiction recovery journeys. Middlesex Recovery PC is noteworthy for its dedication to delivering quality care and a comprehensive support system designed to assist individuals as they work toward recovery.

Out for Good Inc, situated in Dorchester Center, MA, provides outpatient treatment services for those grappling with substance use, catering to both adults and adolescents. The facility is equipped with a focus on various therapeutic methods, including anger management, brief intervention, and cognitive behavioral therapy. Out for Good Inc has developed specific programs aimed at adult men, adult women, and individuals impacted by intimate partner violence, creating a safe space conducive to healing. Their holistic approach ensures personalized care for both male and female clients, emphasizing the distinct needs of each individual. For anyone looking for addiction treatment that prioritizes specialized programs and evidence-based methodologies, this facility is committed to supporting individuals on their journey toward recovery.

SaVida Health, located in Worcester, MA, specializes in outpatient treatment for substance use disorders, emphasizing high-quality care and effective treatment methodologies. The facility offers various services, including outpatient options featuring methadone, buprenorphine, or naltrexone therapies, along with standard outpatient treatment. They also provide specialized programs tailored for adult men and women, as well as those who have faced trauma. In addition to these services, SaVida Health includes offerings such as anger management, brief interventions, and cognitive behavioral therapy to support clients on their journey to recovery. This center is committed to serving adults and young adults of all genders, fostering a comprehensive and personalized approach to each individual's recovery process. For those in search of evidence-based treatment within a nurturing environment, SaVida Health focuses on helping clients attain sustained sobriety.

Spectrum Health Systems Inc, located in Worcester, MA, provides a wide range of substance use treatment options for both adults and children facing co-occurring mental health challenges. The facility offers outpatient care that includes methadone and buprenorphine treatments, as well as cognitive behavioral therapy. To meet the diverse needs of its clients, Spectrum Health has developed specialized programs specifically designed for active duty military personnel, adolescents, and adult men. The clinic employs various tailored approaches, such as anger management and brief interventions, to ensure that each individual receives the personalized care they require. Spectrum Health Systems Inc welcomes both male and female clients and is committed to offering effective, evidence-based treatment aimed at fostering recovery and promoting overall well-being.

Victory Programs Inc, located in Dorchester, MA, focuses on delivering specialized treatment for substance use and transitional housing specifically for women ages 18 and older. The organization provides long-term residential support that emphasizes a variety of therapeutic techniques, including 12-step facilitation, anger management, and cognitive behavioral therapy. The facility addresses the needs of clients who have faced challenges such as intimate partner violence, domestic violence, and sexual abuse. Through its tailored programs, the facility serves a diverse age range of women, from young adults to seniors. Known for its dedication to providing quality care and personalized treatment strategies, Victory Programs Inc serves as a vital resource for women on their journey to recovery and emotional well-being.

Victory Programs Inc, situated in Boston, MA, provides a long-term residential treatment option for adult males struggling with substance use in a secure and nurturing setting. This facility places an emphasis on transitional housing and sober living for those who have encountered intimate partner violence, domestic violence, or sexual abuse. The program utilizes various therapeutic approaches, including 12-step facilitation, anger management, and cognitive behavioral therapy, to effectively meet the distinct needs of each individual. Victory Programs Inc serves a diverse clientele, including adults, seniors, and young adults, while focusing on personalized care specifically designed for male participants. With a strong dedication to delivering specialized services, this facility offers a thorough rehabilitation program aimed at fostering recovery and healing.

Bay Cove Human Services, situated in Boston, MA, offers an extensive selection of outpatient services aimed at individuals seeking detoxification and treatment for substance use disorders. The center specializes in outpatient detoxification, along with providing treatment options involving methadone, buprenorphine, or naltrexone. Their approach emphasizes 12-step facilitation, anger management, and brief intervention strategies. Catering to adult men and women, the facility also addresses the needs of individuals who have faced issues related to intimate partner violence or domestic violence. By serving both adults and young adults across genders, Bay Cove Human Services is dedicated to delivering quality care through personalized treatment plans for those requiring rehabilitation from addiction.

Behavioral Health Network (BHN) is situated in Greenfield, MA, and provides an extensive array of services designed for addiction treatment. The center offers detoxification and substance use treatment, along with specialized support aimed at individuals who are facing both substance use and mental health challenges. BHN offers various treatment formats, including long-term residential care, outpatient services, and options using methadone or buprenorphine, customizing its programs to address the unique needs of each client. The center employs several therapeutic approaches, including 12-step facilitation, anger management, and cognitive-behavioral therapy, fostering a comprehensive treatment environment. BHN has tailored programs designed for adult men, adult women, and members of the LGBTQ community. It serves a broad demographic that includes adults, seniors, and young adults of all genders, focusing on providing individualized care to support each person's journey toward recovery.

Catholic Charities, situated in Leominster, MA, provides long-term residential treatment that emphasizes support for individuals facing challenges related to substance use, as well as those in need of transitional housing. The facility is equipped to address the needs of those who are dealing with co-occurring substance use disorders and serious mental health issues. With therapeutic approaches that include 12-step facilitation, anger management, and cognitive behavioral therapy, the center specializes in supporting adult women who have encountered intimate partner violence, domestic violence, or sexual abuse. The program is designed to cultivate a safe and supportive atmosphere, catering to adults, seniors, and young adults. By focusing exclusively on female clients, Catholic Charities offers a holistic approach to both recovery and emotional healing, ensuring that each individual receives the specialized care they require during their treatment journey.
About Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to provide a comprehensive approach to substance use disorders. Recognized as the gold standard for opioid addiction treatment by the World Health Organization, SAMHSA, and the American Society of Addiction Medicine, MAT has been proven to reduce overdose deaths, improve treatment retention, and support long-term recovery. Massachusetts has been a national leader in expanding MAT access as part of its response to the opioid crisis.
Understanding MAT
MAT works by targeting the brain's opioid receptors or reward pathways to reduce cravings, prevent withdrawal symptoms, and block the euphoric effects of addictive substances. It is not simply "replacing one drug with another" — MAT medications are prescribed at controlled doses that stabilize brain chemistry, allowing individuals to function normally, engage in therapy, maintain employment, and rebuild their lives.
Key principles of MAT:
- Medication addresses the biological component of addiction while therapy addresses psychological and behavioral components
- Treatment should be individualized — no single medication works best for everyone
- Duration of treatment varies; many individuals benefit from long-term or indefinite MAT
- MAT should always include counseling and psychosocial support, not medication alone
- Stopping MAT prematurely is associated with significantly higher relapse rates
Types of MAT Medications
For Opioid Use Disorder
Three FDA-approved medications are available for opioid addiction:
- Methadone: A full opioid agonist that eliminates withdrawal symptoms and reduces cravings. Dispensed through certified Opioid Treatment Programs (OTPs). Requires daily visits initially, with take-home doses earned over time. Most effective for severe opioid use disorder and individuals who haven't responded to other medications.
- Buprenorphine (Suboxone, Sublocade): A partial opioid agonist that reduces cravings and withdrawal with lower overdose risk than methadone. Available as sublingual tablets/films (Suboxone), monthly injections (Sublocade), and implants (Probuphine). As of 2023, any licensed prescriber can prescribe buprenorphine — the previous X-waiver requirement has been eliminated, significantly expanding access.
- Naltrexone (Vivitrol): An opioid antagonist that completely blocks opioid effects. Available as monthly injection (Vivitrol) or daily oral tablet. Requires complete opioid detox before starting (typically 7-14 days). Ideal for highly motivated individuals and those in criminal justice settings.
For Alcohol Use Disorder
Three FDA-approved medications are available for alcohol addiction:
- Naltrexone: Reduces the pleasurable effects of alcohol and decreases cravings. Available as daily oral tablet or monthly injection (Vivitrol).
- Acamprosate (Campral): Helps restore the balance of brain chemicals disrupted by chronic alcohol use, reducing anxiety and insomnia in early recovery.
- Disulfiram (Antabuse): Creates an unpleasant physical reaction (nausea, flushing, headache) when alcohol is consumed, serving as a deterrent. Requires high motivation and compliance.
MAT Availability in Massachusetts
Massachusetts has been a leader in MAT expansion, driven by the severity of the opioid crisis in the state:
- Multiple certified Opioid Treatment Programs (OTPs) provide methadone across the state
- With the elimination of the X-waiver requirement, any licensed prescriber can now prescribe buprenorphine, dramatically expanding office-based access
- Many Massachusetts emergency departments now initiate buprenorphine treatment, connecting patients directly to ongoing care
- MassHealth covers all FDA-approved MAT medications with no prior authorization required
- The state's Bureau of Substance Addiction Services funds MAT services for uninsured individuals
- Mobile MAT units and telehealth prescribing have expanded access to rural and underserved areas
Is MAT Right for You?
MAT may be appropriate if you:
- Have a moderate to severe opioid or alcohol use disorder
- Have experienced relapse after previous treatment attempts
- Want to reduce cravings and withdrawal symptoms while engaging in therapy
- Need to maintain work, school, or family responsibilities during treatment
- Are at high risk for overdose
The decision to start MAT should be made collaboratively with an addiction medicine provider who can assess your specific needs, medical history, and treatment goals. MAT works best when combined with CBT, motivational interviewing, group therapy, and peer support.
Common Misconceptions About MAT
- "MAT is just replacing one addiction with another" — False. MAT medications are prescribed at stable doses that normalize brain chemistry without producing euphoria. They allow individuals to function normally, unlike addictive substance use.
- "You're not really sober if you're on MAT" — This harmful misconception discourages people from seeking effective treatment. MAT is evidence-based medical treatment, just like insulin for diabetes or antidepressants for depression.
- "MAT is a short-term fix" — Research shows that longer durations of MAT are associated with better outcomes. Many individuals benefit from MAT for years, and there is no medical reason to set arbitrary time limits.
- "MAT medications are easy to misuse" — Buprenorphine has a ceiling effect that limits its potential for abuse. Naltrexone has no abuse potential. Methadone is dispensed in controlled settings.
Frequently Asked Questions
How long do I need to be on MAT?
There is no standard duration. Some individuals use MAT for months, others for years. The National Institute on Drug Abuse recommends at least 12 months for opioid use disorder, but many experts support indefinite treatment when it is working well. Tapering decisions should be made carefully with your provider.
Can I still attend 12-step meetings while on MAT?
Absolutely. While some 12-step meetings have historically been less accepting of MAT, attitudes are changing. Many MAT-friendly meetings exist, and SMART Recovery fully supports MAT as part of recovery. The official positions of AA and NA do not prohibit medication prescribed by a doctor.
Does MassHealth cover MAT?
Yes. MassHealth covers all three FDA-approved MAT medications for opioid use disorder and alcohol use disorder without prior authorization. Most commercial insurance plans in Massachusetts also cover MAT under state and federal parity laws.
Can I drive and work while on MAT?
Yes. Once stabilized on MAT, most individuals can safely drive, work, and engage in all normal daily activities. Federal law protects individuals on MAT from employment discrimination under the Americans with Disabilities Act.
What happens if I relapse while on MAT?
Relapse does not mean treatment failure. Your provider may adjust your medication dose, add or change therapy, or modify your treatment plan. The important thing is to continue with treatment rather than stopping MAT, which would increase overdose risk.
For more information about MAT:
- SAMHSA — Medications for Substance Use Disorders
- NIDA — Medications to Treat Opioid Addiction
- ASAM — National Practice Guideline for OUD Treatment
Find MAT providers in Massachusetts through our treatment center directory, or call the Massachusetts Substance Use Helpline at 1-800-327-5050 for referrals.