Medication-Assisted Treatment (MAT) Treatment Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for a comprehensive approach to addiction treatment.
Found 173 treatment centers offering medication-assisted treatment (mat) across Massachusetts.
Last reviewed: March 27, 2026
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Showing 20 of 173 medication-assisted treatment (mat) treatment centers
Aftermath Addiction Treatment Center LLC, located in Wakefield, MA, provides a wide range of treatment options for adults dealing with substance use issues. The center has a particular emphasis on individuals who are facing both substance use disorders and serious mental health conditions. In addition, it addresses severe emotional disturbances in children. Treatment formats offered at the facility include intensive outpatient, outpatient, and day treatment programs. The center employs various therapeutic methods, such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, to create individualized treatment plans that cater to the specific needs of each person. The facility also features specialized programs designed for active duty military personnel, as well as programs tailored for adult men and women. By serving both adults and young adults of any gender, Aftermath Addiction Treatment Center LLC is committed to delivering personalized care aimed at supporting individuals in their recovery process.
BrightView Health, situated in Attleboro, Massachusetts, provides a wide range of addiction treatment services for both adults and young adults. The facility supports individuals through detoxification and various levels of substance use treatment, including intensive outpatient, outpatient, and day treatment options. By employing evidence-based methods such as brief intervention, cognitive behavioral therapy, and community reinforcement with vouchers, BrightView Health ensures that each treatment plan is customized to meet the unique needs of its clients. The center has a specific emphasis on serving adult men and women, including those who have faced challenges related to intimate partner violence. With a commitment to delivering quality care and personalized assistance, BrightView Health strives to support individuals in their journey toward sustainable recovery.
Brockton Neighborhood Health Center, situated in Brockton, MA, provides a broad range of outpatient services focused on substance use treatment. This center is dedicated to assisting adults who face co-occurring serious mental health disorders and children grappling with significant emotional disturbances. It offers various treatment options, including outpatient methadone or buprenorphine and naltrexone therapies, regular outpatient care, and targeted programs for specific populations such as individuals living with HIV/AIDS, those with co-occurring conditions, and pregnant or postpartum women. The treatment methodologies employed at the center encompass brief intervention techniques, cognitive behavioral therapy, and contingency management with motivational incentives. Brockton Neighborhood Health Center caters to both men and women, ensuring that the care provided is tailored to meet the unique needs of both adults and children/adolescents. The facility's commitment to quality and holistic care underscores its dedication to supporting individuals on their journey to recovery.
The Brockton Neighborhood Health Center, situated in Brockton, Massachusetts, specializes in substance use treatment primarily for adults and young adults. This facility offers outpatient services, encompassing treatment options such as methadone, buprenorphine, or naltrexone. Emphasizing relapse prevention, the center adopts an individualized approach to each client's care. Committed to providing quality treatment, the center serves both male and female patients, offering comprehensive support as they navigate their recovery journeys. The tailored programs at the Brockton Neighborhood Health Center are designed to meet the unique needs of each person, assisting them in their pursuit of sustained sobriety.
Casa Esperanza Inc, situated in Roxbury, Massachusetts, provides a wide range of substance use treatment services alongside transitional housing specifically designed for adult women. The facility addresses the complex needs of individuals facing co-occurring substance use disorders and serious mental health challenges, while also offering support for emotional issues in children. Emphasizing long-term residential care, Casa Esperanza employs various evidence-based methods, such as 12-step facilitation and anger management, to deliver tailored and gender-specific care to women in its programs. In addition to its core services, Casa Esperanza has developed specialized programs for active duty military members, survivors of intimate partner violence, and individuals dealing with domestic violence. The facility's approach is inclusive, serving adults, seniors, and young adults alike, and is committed to promoting sustainable recovery through individualized treatment plans that cater to the unique circumstances of each client.
Casa Esperanza Inc, situated in Boston, MA, specializes in providing substance use treatment specifically designed for adult men. The facility offers several types of care, including hospital inpatient treatment, round-the-clock care, and long-term residential programs. Utilizing various therapeutic approaches, the center incorporates 12-step facilitation, anger management, and brief intervention strategies in its treatment plans. This center serves clients who have endured experiences such as intimate partner violence, domestic violence, and sexual abuse. Casa Esperanza Inc is committed to delivering quality care tailored to the needs of adults, seniors, and young adults, ensuring that all clients receive support in a safe environment. For individuals seeking comprehensive addiction treatment that prioritizes individualized care, Casa Esperanza Inc presents a viable option.
Central Mass Clinical Associates Inc, located in Worcester, MA, provides specialized rehabilitation services for individuals facing challenges related to substance use and co-occurring mental health disorders, accommodating both adults and children. The facility emphasizes intensive outpatient treatment, outpatient care, and medication-assisted treatment options, including methadone, buprenorphine, and naltrexone. Their approach incorporates methods such as 12-step facilitation, anger management, and brief intervention to offer tailored support for each individual. In addition to their standard offerings, Central Mass Clinical Associates features distinct programs designed for adolescents and individuals who have experienced intimate partner violence, domestic violence, or sexual abuse. The center serves a diverse population, including adults, seniors, and young adults of all genders, ensuring a holistic and compassionate approach to addiction treatment for those in need.
Situated in Mashpee, Massachusetts, the CHC of Cape Cod Addiction Program specializes in offering extensive treatment for adults dealing with substance use challenges, as well as those experiencing co-occurring mental health conditions. The facility provides outpatient services, which include both methadone and buprenorphine treatment, along with standard outpatient care options. The program employs various therapeutic methods, such as anger management and motivational interviewing, to address the specific needs of its clients, including active duty military personnel, adult men, and women. Designed to assist adults and seniors across all gender identities, this program focuses on delivering effective care that supports individuals as they navigate their recovery pathways.
CleanSlate Centers, located in Hyannis, MA, offers outpatient treatment for substance use disorders, featuring options such as methadone, buprenorphine, and naltrexone. The facility employs motivational interviewing along with relapse prevention techniques and counseling specific to substance use disorders. This approach ensures that each individual receives care tailored to their unique needs. The center specializes in providing support for adults and young adults, accommodating all genders. CleanSlate Centers emphasizes quality treatment through a personalized methodology. This may be a suitable option for individuals or their loved ones seeking effective addiction treatment with a comprehensive and customized focus.
CleanSlate Centers, located in West Springfield, MA, provides outpatient treatment for those dealing with substance use disorders, emphasizing individualized care. Their program offers options such as outpatient methadone, buprenorphine, or naltrexone treatment tailored for both adults and young adults, regardless of gender. The center incorporates motivational interviewing, relapse prevention strategies, and counseling specifically focused on substance use disorders, adjusting its methods to meet the unique needs of each client. CleanSlate Centers demonstrates a commitment to quality care and personal support, making it a noteworthy option for individuals seeking assistance on their recovery journey in a compassionate setting.
CleanSlate Centers, located in Belchertown, MA, provides outpatient treatment for substance use, emphasizing personalized care for both adults and young adults. The center specializes in administering outpatient treatments, including methadone, buprenorphine, and naltrexone, catering to the needs of male and female clients alike. Employing techniques such as motivational interviewing, relapse prevention strategies, and tailored substance use disorder counseling, the facility designs its programs to address the specific requirements of each individual. The center is recognized for its dedication to offering quality, gender-specific care within a supportive atmosphere. For those in search of effective addiction treatment that prioritizes individual needs, CleanSlate Centers presents a thorough and compassionate approach to facilitate one's recovery journey.
CleanSlate Centers, located in Worcester, Massachusetts, provides outpatient treatment for substance use disorders. Their offerings include methadone and buprenorphine treatment, as well as naltrexone therapy. The center emphasizes the use of motivational interviewing techniques, focuses on relapse prevention strategies, and offers counseling specifically designed for substance use disorders. This facility adopts a personalized approach to care, serving both adults and young adults of any gender. By delivering specialized services, CleanSlate Centers strives to assist individuals in navigating their path to recovery from substance use challenges. For those in search of effective and individualized addiction treatment, this center may be a suitable option to consider.
CleanSlate Centers, located in Lynn, Massachusetts, provides outpatient treatment for substance use disorders. The facility offers methadone, buprenorphine, and naltrexone programs, focusing on techniques such as motivational interviewing and relapse prevention, alongside counseling specific to substance use disorders. With an emphasis on personalized care, CleanSlate caters to both adults and young adults, regardless of gender. The center aims to create a supportive atmosphere for those seeking assistance with addiction, prioritizing quality care through individualized treatment plans. For individuals in Lynn looking for a thorough approach to substance use treatment, CleanSlate Centers delivers tailored programs to facilitate recovery.
CleanSlate Centers, located in Tewksbury, MA, offers outpatient treatment for substance use, emphasizing a personalized approach for both adults and young adults. The center provides treatment options that include methadone or buprenorphine, as well as naltrexone, all delivered through methods like motivational interviewing, relapse prevention techniques, and counseling for substance use disorders. This facility is dedicated to developing individualized programs that cater to the specific needs of each client. CleanSlate Centers serves both men and women, creating a supportive environment focused on delivering quality care for individuals seeking comprehensive services for addiction recovery.
CleanSlate Centers, located in Lawrence, MA, provides outpatient treatment for individuals dealing with substance use issues, particularly those seeking methadone, buprenorphine, or naltrexone therapies. The programs offered at this facility incorporate motivational interviewing, relapse prevention strategies, and counseling specifically designed for substance use disorders. By prioritizing personalized care, CleanSlate Centers serves adults and young adults across all genders, ensuring that each individual receives support tailored to their unique needs. This facility creates an encouraging atmosphere for those pursuing recovery from addiction, highlighting their commitment to quality care and a customized approach to treatment. For anyone in need of comprehensive substance use support, CleanSlate Centers stands ready to assist with personalized, effective solutions.
CleanSlate Centers, located in Falmouth, MA, provides outpatient treatment programs specifically designed for individuals facing substance use challenges. The facility emphasizes personalized care, offering outpatient options that include methadone, buprenorphine, or naltrexone treatments for both adults and young adults, regardless of gender. A variety of evidence-based methods are employed at this center, including motivational interviewing, relapse prevention strategies, and counseling focused on substance use disorders. CleanSlate Centers in Falmouth is dedicated to creating customized treatment plans that address the specific needs of each person seeking assistance, making it a resource for those looking to initiate or continue their recovery journey.
Community Health Connections Inc, located in Fitchburg, MA, provides a wide range of outpatient services designed to support both adults and children facing substance use challenges, particularly those with co-occurring mental health disorders. The center's specialized programs address the complex needs of individuals dealing with substance use issues alongside serious emotional disturbances. Among the services offered are outpatient treatment utilizing methadone or buprenorphine, as well as cognitive behavioral therapy, both of which incorporate evidence-based methodologies. This facility employs strategies such as brief intervention and community reinforcement with vouchers to enhance treatment outcomes. The center also recognizes the unique requirements of clients who experience simultaneous pain and substance use disorders, extending its services to adults and seniors across all genders. Community Health Connections Inc prioritizes the delivery of personalized rehabilitation care, aiming to foster recovery and overall wellness for its clients.
Community Health Connections Inc, located in Leominster, MA, delivers specialized outpatient care for both substance use disorders and co-occurring mental health issues in individuals of all ages, including adults and children. The facility employs a range of therapeutic methods, such as cognitive behavioral therapy and community reinforcement strategies, to create personalized treatment plans. Their programs are designed to accommodate clients facing challenges related to mental health alongside substance use, as well as individuals contending with pain and addiction. This center provides a variety of comprehensive treatment options, including outpatient services utilizing methadone, buprenorphine, or naltrexone, and serves a diverse demographic, including adults and seniors of all genders. Emphasizing quality care and tailored support, Community Health Connections Inc aims to be a reliable resource for individuals pursuing their path to recovery.
Community Health Connections Inc, situated in Fitchburg, MA, provides extensive outpatient treatment for substance use that caters to both adults and children who are dealing with serious mental health conditions that occur alongside substance use issues. The facility features targeted programs designed for individuals living with HIV/AIDS, those facing co-occurring mental and substance use disorders, and individuals managing pain combined with substance use concerns. Emphasizing treatment methods such as cognitive behavioral therapy and community reinforcement approaches, the center also administers outpatient options for methadone, buprenorphine, or naltrexone. By serving adults and seniors of all genders, this facility focuses on delivering personalized care and support to individuals navigating their journey towards recovery from addiction and mental health difficulties.
Situated in Tewksbury, Massachusetts, Conexiones provides a range of substance use treatment services designed to meet varying needs. They offer several formats of care, including hospital inpatient services, residential programs, and short-term residential options. By utilizing evidence-based methods like 12-step facilitation, anger management, and brief interventions, the facility focuses on delivering tailored support for each individual. Conexiones serves a wide array of populations, featuring specialized programs for active duty military members, as well as distinct services for adult men and women. The center creates a supportive atmosphere for both adults and young adults of all genders, emphasizing quality care and customized treatment plans to enhance the recovery process for those seeking assistance with addiction.
About Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to provide a comprehensive approach to substance use disorders. Recognized as the gold standard for opioid addiction treatment by the World Health Organization, SAMHSA, and the American Society of Addiction Medicine, MAT has been proven to reduce overdose deaths, improve treatment retention, and support long-term recovery. Massachusetts has been a national leader in expanding MAT access as part of its response to the opioid crisis.
Understanding MAT
MAT works by targeting the brain's opioid receptors or reward pathways to reduce cravings, prevent withdrawal symptoms, and block the euphoric effects of addictive substances. It is not simply "replacing one drug with another" — MAT medications are prescribed at controlled doses that stabilize brain chemistry, allowing individuals to function normally, engage in therapy, maintain employment, and rebuild their lives.
Key principles of MAT:
- Medication addresses the biological component of addiction while therapy addresses psychological and behavioral components
- Treatment should be individualized — no single medication works best for everyone
- Duration of treatment varies; many individuals benefit from long-term or indefinite MAT
- MAT should always include counseling and psychosocial support, not medication alone
- Stopping MAT prematurely is associated with significantly higher relapse rates
Types of MAT Medications
For Opioid Use Disorder
Three FDA-approved medications are available for opioid addiction:
- Methadone: A full opioid agonist that eliminates withdrawal symptoms and reduces cravings. Dispensed through certified Opioid Treatment Programs (OTPs). Requires daily visits initially, with take-home doses earned over time. Most effective for severe opioid use disorder and individuals who haven't responded to other medications.
- Buprenorphine (Suboxone, Sublocade): A partial opioid agonist that reduces cravings and withdrawal with lower overdose risk than methadone. Available as sublingual tablets/films (Suboxone), monthly injections (Sublocade), and implants (Probuphine). As of 2023, any licensed prescriber can prescribe buprenorphine — the previous X-waiver requirement has been eliminated, significantly expanding access.
- Naltrexone (Vivitrol): An opioid antagonist that completely blocks opioid effects. Available as monthly injection (Vivitrol) or daily oral tablet. Requires complete opioid detox before starting (typically 7-14 days). Ideal for highly motivated individuals and those in criminal justice settings.
For Alcohol Use Disorder
Three FDA-approved medications are available for alcohol addiction:
- Naltrexone: Reduces the pleasurable effects of alcohol and decreases cravings. Available as daily oral tablet or monthly injection (Vivitrol).
- Acamprosate (Campral): Helps restore the balance of brain chemicals disrupted by chronic alcohol use, reducing anxiety and insomnia in early recovery.
- Disulfiram (Antabuse): Creates an unpleasant physical reaction (nausea, flushing, headache) when alcohol is consumed, serving as a deterrent. Requires high motivation and compliance.
MAT Availability in Massachusetts
Massachusetts has been a leader in MAT expansion, driven by the severity of the opioid crisis in the state:
- Multiple certified Opioid Treatment Programs (OTPs) provide methadone across the state
- With the elimination of the X-waiver requirement, any licensed prescriber can now prescribe buprenorphine, dramatically expanding office-based access
- Many Massachusetts emergency departments now initiate buprenorphine treatment, connecting patients directly to ongoing care
- MassHealth covers all FDA-approved MAT medications with no prior authorization required
- The state's Bureau of Substance Addiction Services funds MAT services for uninsured individuals
- Mobile MAT units and telehealth prescribing have expanded access to rural and underserved areas
Is MAT Right for You?
MAT may be appropriate if you:
- Have a moderate to severe opioid or alcohol use disorder
- Have experienced relapse after previous treatment attempts
- Want to reduce cravings and withdrawal symptoms while engaging in therapy
- Need to maintain work, school, or family responsibilities during treatment
- Are at high risk for overdose
The decision to start MAT should be made collaboratively with an addiction medicine provider who can assess your specific needs, medical history, and treatment goals. MAT works best when combined with CBT, motivational interviewing, group therapy, and peer support.
Common Misconceptions About MAT
- "MAT is just replacing one addiction with another" — False. MAT medications are prescribed at stable doses that normalize brain chemistry without producing euphoria. They allow individuals to function normally, unlike addictive substance use.
- "You're not really sober if you're on MAT" — This harmful misconception discourages people from seeking effective treatment. MAT is evidence-based medical treatment, just like insulin for diabetes or antidepressants for depression.
- "MAT is a short-term fix" — Research shows that longer durations of MAT are associated with better outcomes. Many individuals benefit from MAT for years, and there is no medical reason to set arbitrary time limits.
- "MAT medications are easy to misuse" — Buprenorphine has a ceiling effect that limits its potential for abuse. Naltrexone has no abuse potential. Methadone is dispensed in controlled settings.
Frequently Asked Questions
How long do I need to be on MAT?
There is no standard duration. Some individuals use MAT for months, others for years. The National Institute on Drug Abuse recommends at least 12 months for opioid use disorder, but many experts support indefinite treatment when it is working well. Tapering decisions should be made carefully with your provider.
Can I still attend 12-step meetings while on MAT?
Absolutely. While some 12-step meetings have historically been less accepting of MAT, attitudes are changing. Many MAT-friendly meetings exist, and SMART Recovery fully supports MAT as part of recovery. The official positions of AA and NA do not prohibit medication prescribed by a doctor.
Does MassHealth cover MAT?
Yes. MassHealth covers all three FDA-approved MAT medications for opioid use disorder and alcohol use disorder without prior authorization. Most commercial insurance plans in Massachusetts also cover MAT under state and federal parity laws.
Can I drive and work while on MAT?
Yes. Once stabilized on MAT, most individuals can safely drive, work, and engage in all normal daily activities. Federal law protects individuals on MAT from employment discrimination under the Americans with Disabilities Act.
What happens if I relapse while on MAT?
Relapse does not mean treatment failure. Your provider may adjust your medication dose, add or change therapy, or modify your treatment plan. The important thing is to continue with treatment rather than stopping MAT, which would increase overdose risk.
For more information about MAT:
- SAMHSA — Medications for Substance Use Disorders
- NIDA — Medications to Treat Opioid Addiction
- ASAM — National Practice Guideline for OUD Treatment
Find MAT providers in Massachusetts through our treatment center directory, or call the Massachusetts Substance Use Helpline at 1-800-327-5050 for referrals.