Rehab Massachusetts Logo

Medication-Assisted Treatment (MAT) Treatment Centers

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies for a comprehensive approach to addiction treatment.

Found 173 treatment centers offering medication-assisted treatment (mat) across Massachusetts.

Last reviewed: March 27, 2026

Want us to find the perfect facility for you?

Call now - it's completely free!

Call (866) 227-1258
24/7 Support
331+ Centers
Filters:

Showing 20 of 173 medication-assisted treatment (mat) treatment centers

Spectrum Health Systems Inc

Spectrum Health Systems Inc, located in Framingham, MA, provides a wide array of outpatient services aimed at addressing substance use disorders alongside co-occurring mental health issues for both adults and children. The facility is equipped to offer specialized programs for individuals affected by intimate partner violence, sexual abuse, or trauma, ensuring that these sensitive experiences are taken into account during treatment. Their therapeutic methods encompass various approaches, including anger management, cognitive behavioral therapy, and brief intervention strategies. The center serves a diverse clientele, welcoming both male and female adults, as well as young adults. Treatment options include standard outpatient care as well as specific outpatient services utilizing methadone, buprenorphine, or naltrexone. Spectrum Health Systems Inc remains committed to delivering both effective and compassionate care, supporting individuals as they progress on their recovery journeys.

Spectrum Health Systems Inc

Spectrum Health Systems Inc, located in Haverhill, MA, specializes in providing comprehensive substance use treatment through various outpatient programs. These programs include the administration of methadone or buprenorphine, as well as naltrexone treatment, coupled with cognitive behavioral therapy to address the psychological aspects of addiction. The facility offers additional services such as anger management and brief interventions, along with customized programs designed specifically for adult women, individuals who have experienced intimate partner violence or domestic violence, and those who have faced sexual abuse. The center serves a diverse population, including both adults and young adults of all genders, with a strong focus on delivering personalized care. By emphasizing evidence-based methodologies, Spectrum Health Systems Inc is committed to fostering a supportive environment that facilitates comprehensive healing and recovery. Their aim is to assist individuals in overcoming addiction, enabling them to build healthier and more fulfilling lives.

Spectrum Health Systems Inc

Spectrum Health Systems Inc, located in North Adams, MA, provides a wide range of addiction treatment services aimed at both adults and young adults. The facility specializes in detoxification, treatment for substance use, and addressing co-occurring disorders. It offers outpatient care that encompasses detoxification as well as methadone and buprenorphine treatment. Additionally, Spectrum Health Systems Inc employs various therapeutic strategies, including 12-step facilitation and anger management, to support recovery. The organization has developed tailored programs to meet the unique needs of different populations, including active duty military personnel and adult men and women. By focusing on individualized treatment plans, Spectrum Health Systems Inc strives to deliver quality care that is responsive to the diverse requirements of those seeking rehabilitation services in the North Adams community.

Steppingstone Inc
New Bedford, MA

Steppingstone Inc, located in New Bedford, MA, provides focused addiction treatment services within a residential environment designed for support and recovery. This facility offers long-term residential care specifically for adult women, including those who have encountered intimate partner violence. The center's programs are tailored to meet individual needs and utilize various methods, such as 12-step facilitation, anger management, and brief interventions, allowing for a comprehensive approach to treatment. The services at Steppingstone Inc extend to active duty military personnel and seniors, reflecting a commitment to addressing the needs of varied age groups. The facility places a strong emphasis on transitional housing and sober living, prioritizing the overall well-being and recovery of its clients. Steppingstone Inc serves as a significant resource for individuals seeking structured and supportive addiction treatment options.

VOA Behavioral Health Services

Situated in Quincy, Massachusetts, VOA Behavioral Health Services provides a wide array of outpatient treatment options targeting substance use and co-occurring disorders for both adults and children. The center offers a variety of specialized services, such as anger management, cognitive behavioral therapy, and brief intervention strategies. Emphasizing personalized care, their programs cater to adolescents as well as adult men and women. VOA Behavioral Health Services is particularly notable for its dedication to delivering quality treatment grounded in evidence-based practices, accommodating adults and seniors of all genders. Individuals looking for regular outpatient care, as well as those in need of methadone, buprenorphine, or naltrexone treatment, can access supportive and compassionate services at this facility.

Framingham, MA

Located in Framingham, MA, 228 COE House provides long-term residential treatment designed for adults struggling with substance use disorders and co-occurring serious mental health conditions, as well as children facing serious emotional disturbances. The facility prioritizes a personalized approach to recovery, employing specialized methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. It features distinct programs tailored for adult women, particularly those who have encountered intimate partner violence or other traumatic experiences. In its efforts to serve a diverse range of clients, including seniors and young adults, 228 COE House emphasizes delivering compassionate and effective care in a secure and nurturing setting, with a strong focus on the needs of female clients.

Plymouth, MA

Anchor House Inc, located in Plymouth, Massachusetts, provides long-term residential treatment specifically designed for adult men facing challenges related to substance use and co-occurring mental health disorders. The facility emphasizes a supportive atmosphere and offers specialized programs for individuals who have endured intimate partner violence, domestic violence, or sexual abuse. Anchor House utilizes evidence-based methods, including 12-step facilitation, cognitive behavioral therapy, and contingency management, to promote holistic healing and recovery. Their gender-specific program is tailored to meet the unique needs of male adults, ensuring that each client receives personalized care and attention. The center's dedication to delivering quality care and specialized services positions it as a valuable resource for those in search of thorough and effective rehabilitation options.

Avanzando Gandara Center, located in Ludlow, MA, provides long-term residential treatment options for adults facing substance use disorders alongside co-occurring serious mental health challenges. The center also addresses substantial emotional disturbances in children. Emphasizing 12-step facilitation, anger management, and brief interventions, this facility is particularly attuned to the needs of adult women who have encountered intimate partner violence, domestic violence, or sexual abuse. With dedicated programs tailored for adults, seniors, and young adults, the center fosters a secure and encouraging atmosphere for female clients in pursuit of recovery. Avanzando Gandara Center is committed to offering thorough and compassionate care, supporting individuals as they navigate their paths toward healing and empowerment.

Behavioral Health Network (BHN), situated in Holyoke, MA, provides an array of services to address substance use disorders while also supporting individuals with co-occurring serious mental health challenges and emotional disturbances in children. The facility offers outpatient treatment options, which include methadone and buprenorphine therapies, along with regular outpatient programs designed to meet client needs. BHN employs various therapeutic approaches, such as 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, targeting adult men, trauma survivors, and those grappling with co-occurring disorders. The center is dedicated to serving adults, seniors, and young adults of all genders, ensuring that its programs are tailored to the unique requirements of each individual seeking care.

Springfield, MA

BestLife, situated in Springfield, MA, provides outpatient rehabilitation services for individuals facing substance use issues along with co-occurring mental health disorders, accommodating both adults and children. The facility is dedicated to delivering personalized care that addresses the unique needs of its male and female clients. BestLife utilizes evidence-based methodologies, including cognitive behavioral therapy, anger management, and the Matrix Model, to facilitate effective recovery strategies. This center emphasizes the importance of individualized treatment plans, creating a supportive and nurturing environment for those aiming to navigate the challenges of addiction and mental health. Clients seeking assistance can expect a compassionate approach that prioritizes their overall well-being throughout the recovery process.

Beth Israel Lahey Health Behavioral Services, situated in Gloucester, MA, provides a range of outpatient rehabilitation services aimed at assisting adults and young adults who are facing challenges related to substance use disorders along with co-occurring mental health issues. The facility has a particular focus on detoxification and substance use treatment, alongside specialized programs designed for individuals experiencing serious mental health conditions. The center utilizes evidence-based approaches such as cognitive behavioral therapy, motivational interviewing, and contingency management to deliver personalized care for adult men and women. Clients can access outpatient detoxification services, along with medication-assisted treatment options that include methadone or buprenorphine, all designed to support their journey toward recovery.

Westborough, MA

Better Life Partners, located in Westborough, Massachusetts, offers specialized rehabilitation services focused on substance use treatment for both adults and young adults. This facility provides various outpatient services, including outpatient methadone, buprenorphine, and naltrexone treatments, allowing for flexible options that cater to individual needs. Their approach incorporates evidence-based methods such as anger management, brief interventions, and cognitive behavioral therapy. In addition, Better Life Partners features specialized programs designed for adult men and women, as well as for clients who are dealing with both mental health and substance use disorders. The emphasis on personalized care reflects their commitment to addressing the unique needs of each client, ensuring that individuals from diverse backgrounds receive appropriate support throughout their addiction recovery journey.

Boston, MA

Bicycle Health, located in Boston, MA, provides outpatient treatment for substance use with a particular emphasis on methadone, buprenorphine, and naltrexone therapies. In addition to regular outpatient care, the facility employs various specialized techniques, which include brief intervention, cognitive behavioral therapy, and strategies for preventing relapse. The center is recognized for its customized treatment programs designed to meet the needs of adults and young adults across all gender identities. Committed to delivering quality care, Bicycle Health focuses on a personalized approach that supports individuals throughout their recovery journey. For those looking for compassionate and effective addiction treatment, this facility offers a range of services tailored to address diverse needs.

Situated in South Weymouth, MA, the Bridge and Perinatal Behavioral Health Programs at this facility provide a range of outpatient services, including detoxification, treatment for substance use disorders, and outpatient options for methadone, buprenorphine, or naltrexone. The center emphasizes tailored interventions, utilizing techniques such as brief intervention, cognitive behavioral therapy, and contingency management along with motivational incentives. With a commitment to addressing the complex needs of individuals experiencing co-occurring mental health and substance use disorders, the facility also offers specialized support for pregnant and postpartum women. It serves both adults and young adults, regardless of gender, focusing on individualized care that fosters recovery and overall wellness in a nurturing environment.

Pittsfield, MA

Situated in Pittsfield, Massachusetts, the Brien Center delivers targeted treatment for substance use issues along with co-occurring mental health services designed for both adults and children. The center emphasizes intensive outpatient and outpatient treatment options, which include programs involving methadone and buprenorphine. A variety of evidence-based therapies are utilized, such as anger management and cognitive behavioral therapy, to support recovery. The Brien Center also features specialized programs aimed at adult men, adult women, and those who have experienced intimate partner violence, ensuring that care is personalized to meet individual needs. By serving adults and young adults of diverse genders, the center is dedicated to providing quality rehabilitation services for individuals seeking support in the Pittsfield area.

Pittsfield, MA

The Brien Center, situated in Pittsfield, MA, offers outpatient treatment for substance use disorders while also addressing co-occurring mental health disorders in adults and serious emotional disturbances in children. This facility employs a variety of effective methods, including anger management, brief intervention, and cognitive behavioral therapy within its regular outpatient programs. Furthermore, it features specialized programs designed for adolescents and individuals who have experienced intimate partner violence, domestic violence, or sexual abuse. Welcoming adults, seniors, and young adults of all genders, the Brien Center is recognized for its comprehensive and empathetic approach, serving as a supportive resource for those in the Pittsfield area seeking rehabilitation services.

North Adams, MA

The Brien Center, situated in North Adams, MA, provides a range of substance use treatment services tailored for both adults and children facing co-occurring mental health challenges. Their outpatient treatment options are designed for individuals seeking medication-assisted therapies such as methadone, buprenorphine, or naltrexone. The center employs evidence-based methodologies, including anger management, cognitive behavioral therapy, and the Matrix Model, to support the unique needs of adult men and women, including seniors. By emphasizing high-quality care and individualized treatment plans, the Brien Center fosters a welcoming atmosphere for clients grappling with co-occurring disorders. Their commitment extends to offering specialized programs that cater to various age groups and genders, aiming to assist individuals on their journey toward sustained recovery.

Situated in Lynn, Massachusetts, BrightView Health provides a wide range of addiction treatment services aimed at both adults and young adults. The center facilitates detoxification and substance use treatment through various formats, including intensive outpatient, outpatient, and day treatment programs. Employing evidence-based methods such as cognitive behavioral therapy, brief intervention, and community reinforcement along with vouchers, BrightView Health customizes treatment plans to meet the unique needs of each individual. Additionally, specialized programs are available for adult men, adult women, and pregnant or postpartum women, ensuring that care is tailored to specific populations. With an emphasis on quality care and personalized support, BrightView Health serves as a reliable option for individuals seeking effective rehabilitation services in a nurturing setting.

Somerville, MA

Caspar Inc, located in Somerville, MA, provides a wide array of long-term residential treatment services geared specifically toward adult men dealing with substance use issues. The facility emphasizes the 12-step facilitation method, alongside anger management techniques and brief intervention strategies, catering to the unique needs of its clients. In addition to residential treatment, Caspar Inc offers transitional housing, a halfway house, and sober living arrangements for individuals who have faced challenges such as intimate partner violence, domestic violence, or sexual abuse. With a commitment to accommodating adult, senior, and young adult populations, this center prioritizes creating a safe and supportive space for male clients who are on their recovery journey. The range of specialized programs at Caspar Inc contributes to its reputation as a reliable option for those seeking assistance in overcoming addiction.

Cambridge, MA

Situated in Cambridge, MA, Caspar Inc is dedicated to offering long-term residential and 24-hour care specifically for adult women dealing with substance use issues. The facility employs methods such as 12-step facilitation and anger management, alongside brief intervention techniques to assist in the recovery process. Notably, the programs are tailored to support adult women who have experienced intimate partner violence, domestic violence, or sexual abuse. This center serves a diverse range of clients, including adults, seniors, and young adults, creating a safe, supportive atmosphere for female individuals seeking specialized assistance. By emphasizing quality care and personalized support, Caspar Inc is committed to helping clients navigate their recovery journey with both compassion and professionalism.

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to provide a comprehensive approach to substance use disorders. Recognized as the gold standard for opioid addiction treatment by the World Health Organization, SAMHSA, and the American Society of Addiction Medicine, MAT has been proven to reduce overdose deaths, improve treatment retention, and support long-term recovery. Massachusetts has been a national leader in expanding MAT access as part of its response to the opioid crisis.

Understanding MAT

MAT works by targeting the brain's opioid receptors or reward pathways to reduce cravings, prevent withdrawal symptoms, and block the euphoric effects of addictive substances. It is not simply "replacing one drug with another" — MAT medications are prescribed at controlled doses that stabilize brain chemistry, allowing individuals to function normally, engage in therapy, maintain employment, and rebuild their lives.

Key principles of MAT:

  • Medication addresses the biological component of addiction while therapy addresses psychological and behavioral components
  • Treatment should be individualized — no single medication works best for everyone
  • Duration of treatment varies; many individuals benefit from long-term or indefinite MAT
  • MAT should always include counseling and psychosocial support, not medication alone
  • Stopping MAT prematurely is associated with significantly higher relapse rates

Types of MAT Medications

For Opioid Use Disorder

Three FDA-approved medications are available for opioid addiction:

  • Methadone: A full opioid agonist that eliminates withdrawal symptoms and reduces cravings. Dispensed through certified Opioid Treatment Programs (OTPs). Requires daily visits initially, with take-home doses earned over time. Most effective for severe opioid use disorder and individuals who haven't responded to other medications.
  • Buprenorphine (Suboxone, Sublocade): A partial opioid agonist that reduces cravings and withdrawal with lower overdose risk than methadone. Available as sublingual tablets/films (Suboxone), monthly injections (Sublocade), and implants (Probuphine). As of 2023, any licensed prescriber can prescribe buprenorphine — the previous X-waiver requirement has been eliminated, significantly expanding access.
  • Naltrexone (Vivitrol): An opioid antagonist that completely blocks opioid effects. Available as monthly injection (Vivitrol) or daily oral tablet. Requires complete opioid detox before starting (typically 7-14 days). Ideal for highly motivated individuals and those in criminal justice settings.

For Alcohol Use Disorder

Three FDA-approved medications are available for alcohol addiction:

  • Naltrexone: Reduces the pleasurable effects of alcohol and decreases cravings. Available as daily oral tablet or monthly injection (Vivitrol).
  • Acamprosate (Campral): Helps restore the balance of brain chemicals disrupted by chronic alcohol use, reducing anxiety and insomnia in early recovery.
  • Disulfiram (Antabuse): Creates an unpleasant physical reaction (nausea, flushing, headache) when alcohol is consumed, serving as a deterrent. Requires high motivation and compliance.

MAT Availability in Massachusetts

Massachusetts has been a leader in MAT expansion, driven by the severity of the opioid crisis in the state:

  • Multiple certified Opioid Treatment Programs (OTPs) provide methadone across the state
  • With the elimination of the X-waiver requirement, any licensed prescriber can now prescribe buprenorphine, dramatically expanding office-based access
  • Many Massachusetts emergency departments now initiate buprenorphine treatment, connecting patients directly to ongoing care
  • MassHealth covers all FDA-approved MAT medications with no prior authorization required
  • The state's Bureau of Substance Addiction Services funds MAT services for uninsured individuals
  • Mobile MAT units and telehealth prescribing have expanded access to rural and underserved areas

Is MAT Right for You?

MAT may be appropriate if you:

  • Have a moderate to severe opioid or alcohol use disorder
  • Have experienced relapse after previous treatment attempts
  • Want to reduce cravings and withdrawal symptoms while engaging in therapy
  • Need to maintain work, school, or family responsibilities during treatment
  • Are at high risk for overdose

The decision to start MAT should be made collaboratively with an addiction medicine provider who can assess your specific needs, medical history, and treatment goals. MAT works best when combined with CBT, motivational interviewing, group therapy, and peer support.

Common Misconceptions About MAT

  • "MAT is just replacing one addiction with another" — False. MAT medications are prescribed at stable doses that normalize brain chemistry without producing euphoria. They allow individuals to function normally, unlike addictive substance use.
  • "You're not really sober if you're on MAT" — This harmful misconception discourages people from seeking effective treatment. MAT is evidence-based medical treatment, just like insulin for diabetes or antidepressants for depression.
  • "MAT is a short-term fix" — Research shows that longer durations of MAT are associated with better outcomes. Many individuals benefit from MAT for years, and there is no medical reason to set arbitrary time limits.
  • "MAT medications are easy to misuse" — Buprenorphine has a ceiling effect that limits its potential for abuse. Naltrexone has no abuse potential. Methadone is dispensed in controlled settings.

Frequently Asked Questions

How long do I need to be on MAT?

There is no standard duration. Some individuals use MAT for months, others for years. The National Institute on Drug Abuse recommends at least 12 months for opioid use disorder, but many experts support indefinite treatment when it is working well. Tapering decisions should be made carefully with your provider.

Can I still attend 12-step meetings while on MAT?

Absolutely. While some 12-step meetings have historically been less accepting of MAT, attitudes are changing. Many MAT-friendly meetings exist, and SMART Recovery fully supports MAT as part of recovery. The official positions of AA and NA do not prohibit medication prescribed by a doctor.

Does MassHealth cover MAT?

Yes. MassHealth covers all three FDA-approved MAT medications for opioid use disorder and alcohol use disorder without prior authorization. Most commercial insurance plans in Massachusetts also cover MAT under state and federal parity laws.

Can I drive and work while on MAT?

Yes. Once stabilized on MAT, most individuals can safely drive, work, and engage in all normal daily activities. Federal law protects individuals on MAT from employment discrimination under the Americans with Disabilities Act.

What happens if I relapse while on MAT?

Relapse does not mean treatment failure. Your provider may adjust your medication dose, add or change therapy, or modify your treatment plan. The important thing is to continue with treatment rather than stopping MAT, which would increase overdose risk.

For more information about MAT:

Find MAT providers in Massachusetts through our treatment center directory, or call the Massachusetts Substance Use Helpline at 1-800-327-5050 for referrals.